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Approach Ganeriwal et al. [17] Song et al. [19] Sun et al. [20] TinySeRSync, Sun et al. [21] Manzo et al. [14]

public: Int64 iMediaSizeInBytes; //Total size of media in bytes. TInt iPartitionCount; //No of partitions on media. TPartitionEntry iEntry[KMaxPartitionEntries]; };

layer timestamping The hardware is programmed to add a timestamp authenticated with a message integrity code (MIC) to every MAC packet transmitted This is especially challenging for the newer radios, such as the ones on the newer-generation MICAz motes, where the time required to authenticate the timestamp can interfere with the transmission rate of the radio The authors propose a prediction-based approach where the authenticated timestamp includes a prediction of the time required to calculate the MIC Through these techniques (see Table 171 for summary), the nodes achieve a suf ciently good local-level synchronization, which is exploited in the second phase The second phase implements a global synchronization using the TESLA broadcast authentication protocol This protocol relies on the loose time synchronization between the nodes, and it uses a unidirectional keychain Messages received need to be stored by the receiver and will be authenticated only after several timeslots.

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; Arnett, G; Hollingshead, M; Driscoll, J S Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activities J Med Chem 1989, 32, 1442 1446 50 Choi, W J; Moon, H R; Kim, H O; Yoo, B N; Lee, J A; Shin, D H; Jeong, L S Preparative and stereoselective synthesis of the versatile intermediate for carbocyclic nucleosides: effects of the bulky protecting groups to enforce facial selectivity J Org Chem 2004, 69, 2634 2636..

The TLocDrv class contains a partition number, iPartitionNumber This indicates the element of the partition array in the associated DMedia object, TPartitionInfo::iEntry[], which holds the data for that partition Local drive requests are speci ed in terms of an offset relative to the start of the partition By retrieving partition information from the appropriate DMedia object, the request is converted into an absolute address on the media device and then passed on to the media driver When a driver or extension registers for a set of local drives, it must also specify the number of associated DMedia objects required Hence, drive registration is also the point at which the DMedia objects are allocated and again, they are never destroyed A peripheral bus controller must specify at least one separate media object for each card slot that it controls.

This prevents an attacker from forging messages, but it opens the doors for a denial-of-service attack The messages received need to be buffered for future authentication; and because the memory of sensor nodes is limited, Mallory can create fake messages, which will not pass the authentication test, but will ll the buffer, preventing the node from receiving legitimate messages To prevent denial-of-service attacks, the authors propose a modi ed version of TESLA To reduce the timeslots when the adversary nodes can ood the node with messages based on captured keys (which the receiver node needs to store for future authentication), TinySeRSync uses an implementation with very short delays r (made possible by the good local synchronization achieved in phase I).

Filoviruses have been categorized by the U.S. government as select agents, possessing the potential for biological weaponization. No effective vaccines or therapeutics are currently available; however, such reagents will be vital to combat prospective mass attacks. A complete understanding of the viral life cycle has been hindered somewhat due to limited availability of viral isolates and containment restrictions. Nonetheless, great strides have been made in understanding the processes of viral entry, replication, and budding, as well as disease pathogenesis. This information has revealed a wide array of potential targets for antiviral therapies, as well as methods by which the most effective vaccination strategies may be achieved. Indeed, a combination of some of these recently explored strategies may prove to be the best defense against a future outbreak. A comprehensive review of recent developments in the eld of lovirology and antiviral research is provided in this chapter. Ebola and Marburg viruses comprise the Filoviridae family of viruses. These lamentous, thread-like virions have a single-stranded, negative-sense RNA genome of $19.0 kb in length. The genome encodes the envelope glycoprotein (GP), the matrix proteins VP40 and VP24, the nucleoprotein (NP), nonstructural proteins VP30 and VP35, and the viral polymerase (L) (as reviewed1). The rst documented reports of Ebola virus occurred in 1976 in two simultaneous outbreaks in Zaire (now the Democratic Republic of the Congo) and Sudan.2 The Zaire and Sudan subtypes of Ebola virus have caused the majority of human outbreaks, whereas the Cote d Ivoire subtype has only been implicated in one human case.3 A fourth subtype, Reston, was identi ed in an outbreak in a primate

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